Patient-specific analysis of the volume of tissue activated during deep brain stimulation
نویسندگان
چکیده
منابع مشابه
Patient-specific analysis of the volume of tissue activated during deep brain stimulation.
Despite the clinical success of deep brain stimulation (DBS) for the treatment of movement disorders, many questions remain about its effects on the nervous system. This study presents a methodology to predict the volume of tissue activated (VTA) by DBS on a patient-specific basis. Our goals were to identify the intersection between the VTA and surrounding anatomical structures and to compare a...
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Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has rapidly emerged as an effective treatment for Parkinson’s disease (PD). However, our understanding of the neural response to DBS is limited, and the mechanisms by which DBS achieves its therapeutic effects remain a mystery. We have developed detailed computational tools to study the effects of DBS on a patient-specific basis. We ...
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Deep brain stimulation (DBS) is an established clinical treatment for a range of neurological disorders. Depending on the disease state of the patient, different anatomical structures such as the ventral intermediate nucleus of the thalamus (VIM), the subthalamic nucleus or the globus pallidus are targeted for stimulation. However, the same electrode design is currently used in nearly all DBS a...
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BACKGROUND Over the last two decades, deep brain stimulation (DBS) has become a recognized and effective clinical therapy for numerous neurological conditions. Since its inception, clinical DBS technology has progressed at a relatively slow rate; however, advances in neural engineering research have the potential to improve DBS systems. One such advance is the concept of current steering, or th...
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The volume of tissue activated (VTA) is a well-established approach to model the direct effects of deep brain stimulation (DBS) on neural tissue and previous studies have pointed to its potential clinical applications. However, the elevated computational time required to estimate the VTA with standard techniques used in biological neural modeling limits its suitability for practical use. The go...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2007
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2006.09.034